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BiologyCell Biology

During Which Phase Do Chromosomes First Become Visible?

Chromosomes first become visibly distinct during prophase as chromatin condenses. They already existed as less compact chromatin before this stage.

Question

During which phase of mitosis do chromosomes first become visible?

(A) Prophase

(B) Metaphase

(C) Anaphase

(D) Telophase

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Evidence boundary

This page uses the standard textbook stages of mitosis and ordinary microscopy. First become visible means that chromatin condenses into distinguishable chromosome structures, not that chromosomes or DNA are created in prophase. Prophase and prometaphase describe landmarks within a continuous process.