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BiologyAnatomy & Physiology

Skeletal Muscles: What Blocks Myosin-Binding Sites on Actin at Rest?

Identify the protein that obstructs myosin-binding sites on actin in relaxed skeletal muscle and distinguish all four options.

Question

In relaxed muscle, the myosin-binding site on actin is blocked by ________.A. titinB. troponinC. myoglobinD. tropomyosin

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Evidence boundary

This answer uses the skeletal-muscle context of OpenStax Anatomy and Physiology 2e, Chapter 10 Review Question 9. The four options are preserved in order. It describes the introductory thin-filament regulatory mechanism and should not be generalized to smooth muscle, which uses a different regulatory system.